Four major issues Pak-US relations, Energy crises, Law and order and National reconciliation ordinance were studied on two mainstream channels, Express and Geo News to explore media public association in the light of media literacy and media technology. Randomly selected bulletins and commentary talk shows for one year have been examined to gauge the role of media education and media technologies on media agenda while a survey to 500 cable television viewers of two news channels has been conducted separately to check the audience’s agenda on these issues. Overall, 156 news bulletins and the same number of prime time talk shows were analyzed in the light of agenda setting and media literacy models. Results have confirmed the strong connections between media’s issues salience and audience’s issue priorities on four understudied issues. Correlations were measured from >0.67 to >0.92 with p value less than .001. The study has further discussed and explored the role and impact of media technologies on the part of media channels while audiences’ level of awareness and understanding on the issues will be analyzed in the light of media literacy and media education.